Assertions

An assertion classifies the clinical significance of a variant-disease associate under recognized guidelines.

This section of the documentation details the knowledge model that CIViC uses for representing assertions. Each page roughly corresponds to a field in the Assertion schema. Note that Assertions share several key fields with Evidence Items, listed on the Shared Fields page along with notes regarding differences in the meaning of those fields between the two entities.

Contents:

• Assertions Overview
• Fields Shared with Evidence
• Associated Phenotypes
  • Curating Associated Phenotypes
• NCCN Guideline
  • Understanding NCCN Guidelines
  • Curating NCCN Guidelines
• FDA Companion Test
  • Understanding FDA Companion Tests
  • Curating FDA Companion Tests
• Summary and Description