Browsing

CIViC provides a series of Browse views for different entity types. These are displayed in the left menu and each provides filterable tables for one of the entities: Assertions, Evidence, Molecular Profiles, Genes, Variants, Variant Groups, Clinical Trials, Diseases, Therapies, Phenotypes, Sources and Variant Types.

Each table includes columns for key fields and, where appropriate, filters and sorting controls for narrowing results to entities of interest. Results may be sorted by more than one column at a time: hold the shift key while clicking on a column header to add stacked sort parameters.

Below each table a paging interface is provided to navigate through larger result sets.

Examples of the kinds of information provided in these tables are provided below.

Gene Table

Column

Description

Name

Gene Entrez Name

Gene Aliases

A list of additional aliases (also from Entrez)

Diseases

List of diseases associated with the Gene

Therapies

A list of therapies (e.g. drugs) associated with the Gene

Variant Count

A count of Variants associated with the Gene

Evidence Count

A count of Evidence Items associated with the Gene

Assertion Count

A count of Assertions associated with the Gene

Molecular Profiles Table

Column

Description

Name

Name of Molecular Profile

Aliases

A list of additional aliases associated with the Molecular Profile

Entrez Genes

Entrez name of associated Gene(s)

Variants

Name(s) of associated Variant(s)

Diseases

List of diseases associated with the Molecular Profile

Therapies

A list of therapies associated with the Molecular Profile

Evidence Count

A count of Evidence Items associated with the Molecular Profile

Assertion Count

A count of Assertions associated with the Molecular Profile

Molecular Profile Score

Score summarizing the amount and strength of evidence curated for the Molecular Profile

Variant Table

Column

Description

Variant

Name of Variant

Variant Aliases

A list of additional aliases associated with the Variant

Entrez Gene

Entrez name of associated Gene

Diseases

List of diseases associated with the Variant

Therapies

A list of therapies associated with the Variant

Variant Group Table

Column

Description

Name

Name of the Variant Group

Variants

Names of the Variants in the Variant Group

Genes

List of Genes associated with the Group

Variant Count

A count of Variants in the Group

Evidence Count

A count of Evidence Items associated with the Group

Evidence Table

Column

Description

EID

Evidence ID of the Item

Molecular Profile

Molecular Profile associated with the Item

Diseases

Diseases associated with the Item

Therapies

Therapies associated with the Item

Description

Description of the Item

EL

Evidence Level of the Item

ET

Evidence Type of the Item

ED

Evidence Direction of the Item

S

Significance of the Item

VO

Variant Origin of the Item

R

Evidence Rating of the Item

Assertion Table

Column

Description

AID

Assertion ID of the Assertion

Molecular Profile

Molecular Profile associated with the Assertion

Diseases

Diseases associated with the Assertion

Therapies

Therapies associated with the Assertion

Summary

Curator’s summary of the Assertion

AT

Assertion Type

AD

Assertion Direction

CS

Significance

CAT

AMP/ASCO/CAP Category

Evidence Count

Count of Evidence Items associated with the Assertion

Source Table

Column

Description

Type

Type of Source (PubMed, ASCO or ASH)

Citation ID

PubMed or ASCO ID or ASH ID

Authors

Authors on the Source

Year

Year of Publication or Conference

Journal

Name of Journal (PubMed) or meeting abstract citation (ASCO or ASH)

Name

Title of the publication (PubMed) or meeting abstract citation (ASCO or ASH)

Evidence Count

Count of Evidence Items associated with the Source